Vincristine chemotherapy may cause constipation; which dietary change is recommended?

• A. High-residue diet
• B. Low-residue diet
• C. Low-fat diet
• D. High-calorie diet

Answer: (A)

Vincristine can slow bowel motility and cause constipation in children. A high-residue (high-fiber) diet provides more stool bulk and helps water stay in the stool, which promotes faster, easier passage through the intestines and prevents hard stools that are difficult to pass. Implementing this means including fiber-rich foods appropriate for the child, such as fruits with edible skins, vegetables, whole grains, beans, and bran cereals, while also ensuring adequate fluids to help the fiber work and prevent gas or cramping. Introduce fiber gradually to avoid discomfort.

A low-residue diet would reduce fiber and worsen constipation, and a low-fat or high-calorie diet does not specifically address bowel movement regularity. So, the best option to counteract vincristine-related constipation is a high-residue diet.